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Search Results for " glucosidase, β, acid "

Targets

4

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T19182 Afegostat D-Tartrate Isofagomine D-Tartrate,D-Isofagomine D-Tartrate Others
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T19181 Afegostat D-Isofagomine,Isofagomine Others
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T23653 Afegostat HCl Afegostat,AT-2101,Afegostat hydrochloride,AT2101
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug fo...
T71476 Afegostat TFA
Afegostat, aslo known as Isofagomine, and AT2101, was an experimental drug for the treatment of certain forms of Gaucher's disease. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05099 GBA/glucocerebrosidase Protein, Human, Recombinant (His) Human HEK293 Cells
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida...
TMPY-01579 GBA3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glyc...
TargetMol