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Cat No. | Product Name | Synonyms | Targets |
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T19182 | Afegostat D-Tartrate | Isofagomine D-Tartrate,D-Isofagomine D-Tartrate | Others |
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity. | |||
T19181 | Afegostat | D-Isofagomine,Isofagomine | Others |
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity. | |||
T23653 | Afegostat HCl | Afegostat,AT-2101,Afegostat hydrochloride,AT2101 | |
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug fo... | |||
T71476 | Afegostat TFA | ||
Afegostat, aslo known as Isofagomine, and AT2101, was an experimental drug for the treatment of certain forms of Gaucher's disease. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a ... |
Cat No. | Product Name | Species | Expression System |
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TMPY-05099 | GBA/glucocerebrosidase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida... | |||
TMPY-01579 | GBA3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glyc... |